R&D Pipeline

Current Research Projects

Project Call Funding Agency Role Activities Execution Period
APTAGASTRO IDI-20230064 Partner

Validate the use of the apMNKQ2 aptamer as a potential antitumor drug in gastrointestinal cancers, specifically pancreatic adenocarcinoma (PCA) and colorectal cancer (CRC).

2023-2024
OLIGOFASTX MIG-20211028 Partner

Develop a sustainable platform for new therapies based on oligonucleotides (ASOs, siRNAs and aptamers for the treatment of rare diseases.

2019-
2024
PHITBAC PLEC2021-007739 Partner

AptusBiotech will be in charge of developing novel aptamers for the detection of specific antibiotics used in clinics

2019-
2024

Relevant previous projects in which the entity has participated

Project Call Funding Agency Role Activities Execution Period
AptaBreast RTC2019-007227-1 Coordinator Mnk1 aptamer for breast cancer novel therapy. Preclinical Trials in animal models. 2020-2023
PrediApt RTC2019-007229-1 Coordinator Development of a Predictive System based on Aptamers in response to Treatment with Platinum Derivatives in Lung Cancer 2020-2023
METASTARG EURONANOMED 2018-045 Partner Selection of aptamers against a lung cancer marker and their use for targeting in drug delivery and thus interrupting metastatic progression. 2018-2021
Aptalung RTC-2017-6597-1 Coordinator Lung Cancer Diagnosis Using Aptamer technology. Applications in analysis of circulating tumor cells (CTCs) and in Apta-histochemistry. 2018-2021
AptaVir RETOS 2016 MINECO (RTC-2016-5302-1) Partner Development and manufacture of portable solutions for direct detection of the Chikungunya virus for rapid diagnosis. 2016–2019
MultiDETECT Programa CDTI-interempresas 2016 EUROSTARS-2 (E9781) Partner Aptamers against proteins of seven porcine pathogens with the aim of developing a multiple diagnostic kit for the detection of respiratory and digestive infections in swine. 2015-2018
ApTOLL RETOS 2015 MINECO (RTC-2015-3741-1) Partner Preclinical development of a molecule based on aptamer technology specific to TLR-4 and applicable in Acute Stroke and Cardiovascular Diseases (Myocardial Infarction). 2015-2017
AptaHCV RETOS 2014 MINECO (RTC-2014-1986-1) Partner Development and validation of an aptamer-based platform for the detection and genotyping of hepatasis C virus.  2014-2017
Subprogramm “Innpacto 2011 IPT-2011-1057-010000 Partner Development and clinical validation of a Kit to diagnose the evolution of intestinal absorptive mass, using innovative technology based on selective aptamers of the APO A-IV protein 2011-2014